Vol. 3, Issue 1, Part A (2026)

Background: Up to 30% of neonates universal agonize from childhood colic, a conjoint, self-limiting illness. As of its difficult causes, it is thought-provoking for doctors to treat and creates a prodigious deal of stress for families. The purpose of this narrative review is to postulate an impression of the furthermost contemporary enquiry on the etiology and evidence-based usage of infantile colic in infants less than four months, with a prominence on consolidative and holistic approaches.

Methods: To bargain germane studies available up until August 2025, a literature search was steered using the Cochrane Library, PubMed, and Scopus databases. Trustworthy clinical endorsements randomized controlled trials (RCTs), and high-quality meta-analyses were given precedence in this appraisal.

Results: Infantile colic has respective dissimilar causes. These include modifications in the instinctive vegetation, visceral reaction, and dysregulation of the gut-brain axis. Dissimilar approaches are used in management. Certain probiotic strains, such as Lactobacillus reuteri DSM 17938, are powerfully reinforced for use in suckled newborns and hypoallergenic formulations for those supposed of having cow's milk protein aversion (CMPA). As a harmless additional method, stomach kneading demonstrations possible. It is yet vital to assure parentages and deliver secondary policies.

Conclusion: Infantile colic administration demands for active, vicarious, and evidence-based policy. The chief goalmouths of maintenance must be to instruction out organic explanations, insult harmless substitute treatments similar acupressure, assume appropriate nutritional or probiotic bacterium interferences, and proposal parent sustenance. Forthcoming educations must emphasis on consistent problem-solving tools and behaviors that board the microbiota.